1️⃣ Roche bought the AI layer for pathology

Roche agreed to acquire PathAI for $750M upfront and up to $300M in milestones. PathAI will sit inside Roche Diagnostics after closing, expected in H2 2026.

💡 Why it matters

This is diagnostics M&A with companion-diagnostic leverage. Roche is buying workflow, AI analysis and biomarker discovery capacity, not another scanner.

Coffee talk

If pathology software becomes part of the companion-diagnostic stack, who still gets to call it just infrastructure?


2️⃣ Pathos bought control of a clinical MET asset

Pathos AI acquired a majority stake in DeuterOncology, adding DO-2, a phase 1 third-generation MET kinase inhibitor for MET-altered cancers.

💡 Why it matters

The asset is early, but the angle is concrete: an oncology platform using its own model to pick and buy clinical assets, then run development around them.

Coffee talk

Does this prove AI can source oncology assets, or just that someone finally bought a decent MET program with better tooling?


3️⃣ Merck closed the Terns bet

Merck completed its acquisition of Terns after a $53-per-share tender offer, taking in TERN-701, an oral allosteric BCR::ABL1 inhibitor for CML.

💡 Why it matters

This turns a March deal into owned pipeline. Merck is accepting a near-term R&D charge to add a hematology asset with Breakthrough Therapy status.

Coffee talk

How many more early oncology assets does Merck need before Keytruda feels less like the clock in the room?